Medically reviewed by Dr Diana Chan Xin Hui, Anaesthesiologist & Pain Specialist (MBBS, MMED (Anaesthesia), MCI, FAMS, GDA, EDRA, FIPP). Last Updated: July 14, 2026


Dr Diana Chan is a Pain Medicine Specialist with over 20 years of experience and more than 2,000 pain procedures performed. She is the former Head of the Department of Pain Medicine at Singapore General Hospital and founder of the SingHealth Duke-NUS Pain Centre. She treats patients with postherpetic neuralgia using a personalised combination of medications, nerve-targeted therapies, and minimally invasive interventional pain procedures to help relieve persistent nerve pain and improve quality of life.
Shingles, medically known as herpes zoster, is caused by reactivation of the chickenpox virus (varicella-zoster virus), which can lie dormant in the nerves for decades before flaring up as a painful, blistering rash, usually in a band on one side of the body. Postherpetic neuralgia is the nerve pain that persists after the shingles rash has healed. It occurs because the virus, in the process of reactivating, can damage the affected nerve fibres, causing them to continue sending pain signals even after the skin has recovered.
Not everyone who gets shingles develops postherpetic neuralgia, but for those who do, the pain can be significant and long-lasting, which is why it’s treated as a distinct condition in its own right, not just “leftover” shingles.
Postherpetic neuralgia pain is typically described as:
Postherpetic neuralgia’s duration varies considerably from person to person.
If you’re still experiencing significant pain three months after your rash healed, it’s worth having it properly assessed rather than assuming it will simply fade with time.
Anyone who has had shingles can develop postherpetic neuralgia, but certain factors make persistent nerve pain more likely. You may be at higher risk if you have one or more of the following:
Because age is the single biggest risk factor, and shingles vaccination reduces both the risk of shingles and the risk of postherpetic neuralgia if shingles does occur, vaccination is worth discussing with your doctor, particularly for adults over 50.
A typical assessment includes:
Confirming the pain is in the same distribution as a prior shingles rash, understanding how long it has persisted, and how it’s affecting sleep, clothing tolerance, and daily activities.
Checking the affected skin for scarring consistent with prior shingles, and assessing sensation in the area, including testing for allodynia.
Ensuring the pain pattern is consistent with postherpetic neuralgia rather than another nerve or musculoskeletal condition, particularly important if the rash history is unclear or the pain has spread beyond the original area.
Using this to guide which combination of treatments is likely to help most, since postherpetic neuralgia varies widely in severity between patients.

Dr Diana Chan combines advanced interventional pain techniques with personalised treatment plans to help manage postherpetic neuralgia. Every treatment is tailored to your symptoms, pain severity, and overall health, with minimally invasive options considered whenever appropriate.
First-line medications for postherpetic neuralgia include gabapentinoids (such as gabapentin or pregabalin) and certain tricyclic antidepressants, both of which work on nerve pain signalling rather than general pain relief.
For pain localised to a specific area of skin, topical treatments such as lidocaine patches or capsaicin preparations can be applied directly over the affected area, often used alongside oral medication with fewer systemic side effects.
Targeted injections around the affected nerve can reduce pain signalling and provide meaningful relief, particularly useful when oral medication alone isn’t providing adequate control or when a faster reduction in pain is needed.
For persistent, well-localised postherpetic neuralgia pain that hasn’t responded adequately to medication, radiofrequency ablation can be used to reduce pain signalling from the affected nerve, offering longer-lasting relief for suitable patients.
For more severe or long-standing postherpetic neuralgia that hasn’t responded to other treatments, neuromodulation techniques can help modulate how pain signals are processed, offering an option for patients whose quality of life continues to be significantly affected.
Many patients understandably look into natural or supplement-based options, particularly if they’ve found prescription medications come with side effects that are difficult to tolerate. It’s worth being clear-eyed about what the evidence actually supports:
If you’re considering a supplement or natural remedy, it’s worth mentioning it during your consultation, partly to check there’s no interaction with other medication, and partly so your treatment plan can be adjusted with a full picture of what you’re taking.

Many patients are told to simply “wait it out” after shingles, and while some improvement is expected over time, postherpetic neuralgia is often under-treated rather than untreatable. A pain specialist becomes particularly valuable when:
A pain specialist with experience in neuropathic pain can offer targeted treatments like nerve blocks, radiofrequency ablation, and neuromodulation that go beyond what’s typically available through general medication management alone.
Dr Chan’s approach is shaped as much by personal experience as clinical training, including her own long-term shoulder injury and caring for her father through cancer-related pain. That experience underpins a philosophy centred on three things: an accurate diagnosis before any treatment is proposed, using the least invasive effective option first, and treating pain in the context of a patient’s overall quality of life, not just a symptom to be suppressed.

Specialist in Postherpetic Neuralgia Pain
More Than 20 Years of Pain Medicine Experience
Precision-Guided Nerve Blocks & Injections
Focus on Non-Surgical Relief
Singapore's Only Female Private Pain Specialist
Does postherpetic neuralgia go away on its own?
For many patients, postherpetic neuralgia gradually improves over months, and a significant proportion see substantial improvement within a year. However, some patients experience pain for longer, particularly if they’re older or had more severe shingles, which is why ongoing pain is worth treating rather than only waiting for it to resolve.
Can postherpetic neuralgia come back after it's gone?
Once postherpetic neuralgia has fully resolved, it doesn’t typically return unless a person develops shingles again in the same or a different area, which is uncommon but possible, especially in those with weakened immunity.
Is postherpetic neuralgia linked to age?
Yes, age is the single strongest risk factor for developing postherpetic neuralgia after shingles, with risk increasing substantially after age 50 and continuing to rise with age. This is also why shingles vaccination is particularly recommended for older adults.
Does the shingles vaccine help prevent postherpetic neuralgia?
Shingles vaccination reduces the risk of developing shingles in the first place, and in those who do get shingles despite vaccination, it’s associated with a lower risk of developing postherpetic neuralgia or having it be severe. It’s worth discussing vaccination status with your doctor, particularly if you’re over 50 or have risk factors for shingles.
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